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Research every candidate against your criteria.

Research drugs, companies, and trials against consistent criteria, with evidence and open questions beside each answer.

Research a question across your candidate set

Your research columnWhere is the evidence limited?
CandidateClinical benefitEvidence limits
DupilumabExacerbations + lung function
MepolizumabExacerbations
Select an answer to inspect the evidence.
Evidence summary

No significant between-group difference in quality of life or symptoms.

Turn your next screening question into a research column.

Add a column for clinical differentiation, evidence gaps, or fit with your target product profile.

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Filter by indication, mechanism, stage, and other structured fields before adding your research columns.
Inspect the reasoning
Open a cell to review supporting quotes, evidence ratings, and research steps.
Your next research column

Does the evidence fit our target product profile?

Our criterion: reduce exacerbations, with quality-of-life differentiation assessed separately.

Maven researches each row
Mepolizumab · Example team assessment

Quality-of-life differentiation remains unresolved.

The exacerbation result addresses our stated criterion. MATINEE did not establish a quality-of-life or symptom benefit.

“Between-group differences in measures of health-related quality of life and symptoms were not significant”
Sciurba et al. · NEJM 2025 · Abstract, Results ↗

Compare the findings and the questions still open.

Smart TableCOPD · Competitive assessment

Compare dupilumab and mepolizumab. Where does the clinical evidence support differentiation?

Scroll across to compare all columns →

Drug & mechanismWhich outcomes improved?Where is the evidence limited?What should we investigate next?
DupilumabIL-4Rα antibody

Fewer exacerbations and better lung function.

BOREASNOTUS
Quality-of-life results differ between the two trials.Trial-specific findingsHow consistent is the benefit across endpoints and patient groups?Compare the primary publications
MepolizumabIL-5 antibody

Fewer exacerbations and a longer time to the first event.

MATINEE
No significant quality-of-life or symptom benefit.Direct evidence · MATINEEDoes an exacerbation benefit address the team’s target product profile?Apply your assessment criteria

Investigate the candidates your comparison surfaces.

Bring the criteria behind your next asset screen.